What if the interventions promoted as anti-aging and weight loss solutions could have unintended consequences for mitochondrial health & longevity? This conversation between neurosurgeon Dr Jack Kruse and health vlogger Andreas Christou challenges conventional thinking about what drives metabolic health, which should fascinate those interested GLP-1s, peptides, longevity and quantum biology – but it should really be of interest to everybody, when one considers that cancer is a metabolic disease.
Contrary to mainstream medicine, Dr Kruse believes that the local magnetic field in which you live controls the biochemistry that’s possible in your body and if this isn’t taken into consideration, supplements and medications can have adverse effects.
Dr Kruse explains his perspective on how mitochondrial electron flow, magnetism and sunlight influence human biology and why he believes exogenous compounds like GLP-1s, insulin, peptides and HRT can be harmful when the local biological environment of the patient is compromised.
By “compromised”, he appears to be referring to the magnetic fields corresponding to the High-Declination Areas of the Earth, where the angular difference between true Geographic North and Magnetic North is very large, such as the Arctic and the Antarctic and high-latitude landmasses, like Alaska and Siberia. The further you travel from the Equator and the closer you get to the magnetic poles, the wider the angle of declination becomes.
There’s also the South Atlantic Anomaly near the Equator off the coast of Brazil, causing a declination greater than 20° West in parts of that country.
Dr Kruse seems to suggest that areas of Zero or Low Declination, where Magnetic North and true Geographic North align perfectly are areas where one may see less adverse events with drugs. This is represented as the bright green line in the map below that currently traces through the central US, Central America, where he lives in El Salvador, Chile, Argentina, Great Britain, Spain, looping around the northern half of the African Continent, across India, Western China, Siberia, Western Australia and Indonesia.
IMAGE: Map of Earth's magnetic field declination.
Dr Kruse says:
“If you live in a magnetically-declined area, let’s make it simple, the SAA [South Atlantic Anomaly] or say the Desert [Southwestern US], because most people know that those two places have weak magnetic fields, this is where GLP-1 drugs and the use of peptides, supplements, or drugs are the most dangerous, when you understand this process.
“Does that imply that people that live, say, in a decent magnetic field that has a good horizontal field, kind of like El Salvador does, that they could tolerate the use of peptide supplements and certain drugs? The answer is yes.
“Doesn’t mean it’s a smart thing to do, because if the doctor, functional medicine guy, or, you know, the Ben Greenfields of the world get on a podcast to tell you to use this supplement, if they don’t have the basics of the biophysics down that I just gave you in the beginning of this podcast, and you don’t understand the theory of reflexivity of how things really work, you could set yourself up for a huge problem. And then it’s much more obvious why I think there’s a huge problem with other things.”
Dr Kruse calls GLP-1 the “most abused peptide right now” and he tells Andreas, “The use of the GLP-1 drugs will take 10 to 20 years off of your life, if you really understand the mechanism behind it.”
Dr Kruse continues:
“Insulin and GLP-1 drugs, all of them, they’re celebrated specifically for dropping circulating blood glucose numbers on a piece of paper for lab core, OK?
“But in my quantum decentralized framework, forcing a high chemical load of insulin or synthetic secretogue proteins, peptides, in a field that’s deficient of magnetism along the inner mitochondrial membrane in a low voltage cell is an act of thermodynamic vandalism.
“It is completely quantum coherent to understand that the use of insulin is a high flux substrate that’s designed to ram and flood the upper respiratory chain, Complex I, II, and III, and this changes the topology – remember, that’s the spin state – and this stimulates a terminal Marcus inversion event, which you know as another term, Andreas, that’s called the Warburg shift. That’s what a Marcus inversion event is in biophysics, and most people don’t know this, OK? [i.e., cancer]
“So when centralized medicine applies exogenous insulin or GLP-1 receptor agonist peptides to override a cell that has no voltage, they are treating blood glucose on a piece of paper, they have no understanding that they are using a biological or biochemical sledgehammer to blast more fuel and electrons with the wrong spin through quantum circuit breakers that have already been tripped by a poor decision by the patient to live in a magnetically-declined area.
“This is the reason why I always tell people if you use insulin or GLP-1s in diabetics long enough, you will destroy their longevity by one to two decades. It has nothing to do with treating their blood glucose, because that’s not the problem, OK? That’s the story on those drugs…
“There’s now over 6,000 lawsuits in GLP-1 users because of things like gastroparesis. So what does this mean that people need to understand? When you use any type of peptide, if you don’t have the quantum background that I just gave you in just this one disease, this means that GLP-1 drugs are capable of completely never stopping the problem. Because as long as you are forced to live in a Marcus inversion event, you continue to destroy tissue. It loses its quantum coherence.
“To have quantum coherence in a tissue requires you be in a triplet state. You can never enter the triplet state on these peptide drugs. So when you understand this, you begin to understand why there’s 6,000 lawsuits, because the people that are using these drugs that live in a magnetically-declined zone that already have the pre-existing problem, they can never talk to their nucleus again. That’s the reason why you see Ozzy Osbourne’s daughter look the way she does. This is the reason why you see so many people have the faces that they have when they use GLP-1 drugs.
“Now, what you should understand, because I want to be very clear about this, because I’m painting the worst case for you, are there people that use these drugs that live in a magnetically-decent area that the drugs won’t cause a long-term effect? The answer is yes…
“The thing I want to be clear about, because we spent the time here using GLP-1 agonists as the idea, this is true with BPC-157, CJC-1295, ipamorelin, penealon, all of these drugs, they all have the same effect.
“So you have to realize that the influencer market, the functional medicine market, the longevity market, they use lab tests and performance goals as their bottom line. They do not use quantum mechanics in your inner mitochondrial membrane.
“This is the reason why the biohacking and anti-aging paradigm is so deadly to people’s longevity, because they don’t understand that time, lifespan, healthspan is a function of magnetic sensing in the inner mitochondrial membrane.
“And when you begin to understand really what I’m saying, that that inner mitochondrial membrane really is a time machine for entropy production, it not only pays attention to the electric fields, but also the magnetic fields. And the magnetic fields right now are the things that are varying on a planetary basis for so many people, the electric and magnetic fields from EMF devices and things like that, they play a focal role but we’re talking about a global role.”
Of course, I’m not a neurosurgeon like Dr Kruse and I didn’t go to years of medical school or have years of clinical practice, so I don’t claim to understand all of this but I’ve transcribed the first 25 minutes of this podcast and I’ve linked some diagrams and articles to the complex scientific terms he uses and I’ve gained at least a superficial understanding of aspects of biophysics and quantum biology, where before I had none.
I invite you to not be intimidated by the highly technical language used here and to listen and to skim over the images below and click through the links that pique your interest, because learning is fun!
PARTIAL TRANSCRIPT
Andreas Christou: This is the Fitness Wisdom Podcast. Dr Jack Kruse, welcome back to the Fitness Wisdom Podcast. Thank you for being here.
Dr Jack Kruse: No problem.
Andreas Christou: So today, we’re going to be dissecting and exposing maybe one of your favorite subjects, which is peptides, GLP-1 supplements, hormone therapy, and all that stuff.
You see, a lot of people that are getting injured by using these things, especially when they don’t know how to use them, because they’re hearing biohackers, influencers, and influencer doctors online recommend these things.
And people are going out there on the Dark Web or whatever to find these peptides and supplements and so on, which are actually causing them more harm than good. This is why we’ve got you on today to dissect and expose what this is actually doing to the body through a biophysics lens, because people just think, you know, they look at the biochemistry and they assume that everything is the same, everything outside of the body is the same as the endogenously-produced thing of the body, when we know that that’s actually not the case.
But do you think it would be appropriate to start maybe from your banned TEDx talk?
Dr Jack Kruse: If you really want to go to the tip of the needle, you should start with the most abused peptide right now, and drug, which is the GLP-1 drugs. And the thing that makes me, probably really controversial is my take that the use of the GLP-1 drugs will take 10 to 20 years off of your life, if you really understand the mechanism behind it.
Because I think when you understand the GLP-1 story, you understand the very precision biophysics. And then, I think talking about magnesium, talking about supplements, talking about other things becomes much easier to understand, because then you have the basic mechanism down.
Andreas Christou: Alright, let’s do it then. Let’s talk about the GLP-1s. I think that that’s a really big deal. A lot of people are using this in the name of beauty and aesthetics, but it turns out that it’s literally ruining their biology. You can see it like on the outside of their body, right? So you can imagine what’s going on on the inside. So maybe let’s dissect that. Why is that such a big deal? Why is it such a problem?
Dr Jack Kruse: Well, the first thing we have to do with this one, we have to talk about diabetes from a quantum perspective, I mean, biophysics. So what is the effective defect in all diabetics? It doesn’t matter if you’re Type 1, Type 2, LADA, it doesn’t matter. The single most important thing for you to understand is Complex I, II and III have blocked electrons.
That’s the issue. And then what is the consequence of this? The consequence of this is that you lose the superoxide pulse that’s present in the mitochondria that’s made from oxygen at these levels.
So when you have a blocked Complex I, II and III, what happens? This causes a real problem in the mitochondria, itself, in the IMM [Inner Mitochondrial Membrane].
IMAGE: Inner Mitochondrial Membrane
Dr Jack Kruse: Why? Because the flavin, semiquinone, and superoxide have a pair. They’re like the magnetic pair that you remember and the magnetic compass in the eye. This is the correlate to us in humans, OK?
IMAGE: Flavins
IMAGE: Semiquinone
Dr Jack Kruse: So because the flavin, semiquinone, and superoxide have a pair of electrons, they’re two unpaired, this means by definition they must obey the laws of quantum spin preservation. This is the idea that nobody in central and functional medicine understands, because they don’t understand quantum mechanics and physics well enough.
IMAGE: Quantum spin
Dr Jack Kruse: So when you have this blocked state of electrons in Complex I, II and III, it constantly converts the singlet state, which is opposite-spin electrons, to the triplet state, which is parallel spins. And it turns out that the lifetime of these subatomic particles and their behavior dictate the final chemical output in the system.
IMAGE: Singlet state
Dr Jack Kruse: So let me say that again: This implies that the magnetic field that you live in essentially controls the biochemistry that’s possible in your body. Why? Because remember, you know that superoxide is a free radical. Free radicals all have unpaired electrons.
And it turns out that all free radicals have an EPR pulse, meaning they give you a different pulse in different magnetic fields. That’s the whole point of what the mitochondria is really doing.
IMAGE: Protonation
Dr Jack Kruse: And the reason why this is a big deal and the reason I asked you to start this podcast here, because when you start with that as the cornerstone, you begin to realize what I just said is a paradigm-breaker for central and functional medicine.
It means that the singlet path for electrons that are blocked in the first three complexes always lead to hydrogen peroxide. And it turns out if the spins are anti-parallel, which is singlet, the radical pair can undergo a second electron transfer, or what we call a protonation, that leads to a safe version of hydrogen peroxide.
IMAGE: Protonation
Dr Jack Kruse: The problem is in baseline biology, hydrogen peroxide is relatively stable. It coordinates healthy cell proliferation, wound healing, stem cell proliferation, things like that. It’s generally a good thing. The triplet path, which is through superoxide generation, if the spins flip into a parallel state, they are forbidden from making the same bonds that happens in the triplet state.
So when you begin to understand that these two states are affected by the magnetic field that you’re in, you got to ask the question in a diabetic, “Does this fundamentally mean that Jack is saying that altered magnetism is the key finding in diabetics?” And the answer is “Yes”, that’s the case. And this becomes a really big deal when we talk about the use of GLP-1 peptides.
So now, I want to focus completely on where the rubber meets the road for diabetes in quantum mechanics: So diabetics become trapped in what we call a Marcus inversion state. And this means they have a profound absence of superoxide at the main respiratory nodes that we talked about. And in a Marcus inverted region, the thermodynamic driving force overreadies the reorganization energy that’s present there.
IMAGE: Marcus theory
Dr Jack Kruse: And what does this do? It causes the electron transfer rate between, say, NAD [Nicotinamide Adenine Dinulceotide] and oxygen to go almost to near zero. And when this is blocked, you face a severe free radical famine inside the matrix.
IMAGE: NAD+
Dr Jack Kruse: This is why I said to you in the beginning of this story that diabetics have a lack of superoxide to generate the current along the inner mitochondrial membrane.
And you know that current, from previous podcasts we talked about is about 30 million volts, if you believe the work of Nick Lane. So let’s talk about the consequences, now of superoxide loss of signal.
First one, you lose mitoception, meaning the mitochondria no longer can send out proper signals to the genome, also to water, also to everything in the cell. So that’s consequence one.
The physics barrier, the electron hits a quantum wall. When it gets stalled, superoxide cannot form at any of the complexes. And this blinds the nucleus. In other words, the nucleus loses its native mitoception signals. When it loses it, you have a signal void.
Since the nucleus receives no data, it cannot calibrate genes to respond in proper circadian fashion. This is why diabetics stall in all of their biochemistry and why their longevity is affected. Because the main line in the IMM is inverted and silent, meaning the voltage is dropped.
The cell must deploy alternative situations to stay online to maintain the charge. So what’s the missing spark that happens when superoxide pulse is gone from a biophysics standpoint? It uses an external loop, and that’s called xanthine oxidase. And what does xanthine oxidase allow the mitochondria to do? It allows to make superoxide externally without food electrons.
IMAGE: Xanthine oxidase
Dr Jack Kruse: So what is the direct bypass? Xanthine oxidase shuttles electrons straight to the reduced portion of cytochrome c oxidase.
IMAGE: Cytochrome c oxidase, aka Complex IV
Dr Jack Kruse: And what does this allow it to do? To spin the ATPS motor.
IMAGE: ATP Synthase Motor
Dr Jack Kruse: What does this do? Complex IV [aka cytochrome c oxidase] keeps running without any food calories.
This is why diabetics get gout so often. So people who get gout get told a variety of bullsh¡t. Gout is a sign that you have lost your superoxide pulse. It’s a really bad warning that there’s a problem in there.
So when you understand that this is a metabolic trap in diabetics, you get, when xanthine oxidase is upregulated, you get a huge uric acid surge. This surge is protective, OK? And you have to understand that when uric acid goes up, especially when you’re in a bad magnetic field, these crystals can – I should say, uric acid – can form crystals inside the cell that causes problems.
When those crystals solidify, because the dielectric constant of water decreases, an inflammasome is triggered. That inflammasome pathway is the NLRP3 pathway, and this causes a unified disease pathway in diabetes, OK? This explains why diabetics often get gout.
And then, you got to ask the next question that’s present in centralized and functional medicine, because you know the functional medicine guys always try to tell you that insulin resistance is a big deal. And you know that centralized medicine, especially in type 1 diabetics, often uses insulin.
So ask yourself the next question when you know that Complex I, II and III, the thing that starts this, you can’t move electrons, you give someone who’s diabetic insulin, how does this fit into this quantum story?
So insulin increases the bottleneck blockade in Complex I, II and III. Why? Because it’s forcing more electrons in through broken Complex I and II. So when you understand that you have a bottleneck and you keep trying to put cars through the tunnel, what happens? This causes a massive Marcus inversion in the IMM. What does that do? It flips all triplet state electrons to singlet state and causes major problems.
Now, when you understand that insulin causes this, now we come to Andreas’s big question: “Jack, what do the GLP-1 peptides do to diabetics if you know this mechanism?”
…India created 170, 180 million diabetics, literally in 25 years when things changed. Well, it turned out the Agonic Line from the magnetic field also changed, where? Facebook and Google moved all their call centers. And this effect is why they created the largest amount of diabetics in a very short period of time.
Why? Because a focal effect would have to be similar to everybody. When you see a huge group of people, this happened to, you know, that it’s got to be a much more global effect. And that forces you to go look for that story.
So I want to make sure that everybody who listens to this podcast understand clearly what I’m saying. I want you to understand why I say the things I do, because if you don’t understand that, that radical pair mechanism between flavin semiquinone and superoxide – just so the people who are out there who are not science people – this is FAD with one electron negative and oxygen O2 with a negative electron. This is the radical pair checkpoint. That is the key for humans.
Now, if you read Jim Al-Khalili’s book, you learn about the European robin, how they use magnetic sensing in the eye. I’ve taught my people about one of the things that they use to do this. This is in a godwit bird.
As my example on Patreon, they use something called pecten oculi, which is a melanin tissue. What is the checkpoint that this quantum information that gets blinded feeds into? You may be surprised to hear this. This is neuropsin, OPN5.
And if you look at any of the slides that I’ve posted, any of the blogs, this directly opens the idea to the Marcus inverted region that occurs on the inner mitochondrial membrane.
So when I explain to you that neuropsin with this topology slip on electron spin acts as a dual axis quantum field transistor, this is exactly what the European robin that the Klitschko’s found are doing. The difference is birds have it in their eyes, because they fly when they’re disconnected from the magnetic field. So they use the magnetic field around them to make the decision. We use Complex I, II and III to do it as humans. And that’s the key.
And when you understand this, you go, “OK, so that information that allows the inner mitochondrial membrane to talk to our nucleus has to use a gatekeeper. The gatekeeper is neuropsin. And norepsin acts as the inner system crossing gatekeeper.
And what part of physics does this link to? This is phase two. This is now I’m breaking down for you what happens when you have this problem in the beginning.
It’s called the Zeeman effect. Everybody should look up the Zeeman effect when you hear this podcast, because I know this is difficult science, but the science is really important for you to understand. How many charlatans are present in the functional allopathic and biohacking world?
Because the Zeeman handshake, when it’s in reference to neuropsin functions as a non-equilibrium quantum field effective transistor. What does that mean? Everybody knows from my slides that I put out that 380 nanometer UVA light excites neuropsin, OK? Everybody got that.
Neuropsin is an option that has a weakly covalent vitamin A retinal bond, and this generates a local piezoelectric field that stabilizes the Zeeman splitting effect that happens in every iron hemoprotein in your body.
Let me repeat that. It generates a piezoelectric field in every cell of your body that stabilizes the Zeeman splitting effect in all iron heme proteins.
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