Published by NatureVideoChannel
September 6, 2012

ENCODE, the Encyclopaedia of DNA Elements, is the most ambitious human genetics project to date. Remarkably, ENCODE has so far explained 80% the biochemical functions of the 3 billion letters described by the Human Genome Project in 2000.

This information is helping us understand how genomes are interpreted to make different types of cells and different people — and crucially, how mistakes can lead to disease.

In this video, ENCODE’s lead coordinator, Ewan Birney, and Nature editor Magdalena Skipper talk about the challenges of managing this colossal project.

To read the research papers and more, visit

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